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AstraZeneca vaccine - 10 things to know with detail

• What is the AstraZeneca vaccine?
• The AstraZeneca vaccine is a COVID-19 vaccine developed by AstraZeneca in collaboration with the University of Oxford. It is an adenoviral vector vaccine that uses a harmless virus to deliver genetic material from the SARS-CoV-2 virus to stimulate an immune response.
• Efficacy of the vaccine
• Clinical trials have shown that the AstraZeneca vaccine has an average efficacy of around 70%, with some studies reporting higher efficacy rates depending on the dosing regimen used.
• Storage and handling requirements
• The AstraZeneca vaccine can be stored at standard refrigerator temperatures of 2-8 degrees Celsius, making it easier to distribute and administer in comparison to other COVID-19 vaccines that require ultra-cold storage.
• Dosage and schedule
• The AstraZeneca vaccine is administered in two doses, with the second dose typically given 4-12 weeks after the first dose. The recommended dosage is 5 ml per dose.
• Side effects
• Common side effects of the AstraZeneca vaccine include pain and swelling at the injection site, fatigue, headache, muscle aches, and fever. These side effects are usually mild to moderate and resolve within a few days.
• Age groups and eligibility
• The AstraZeneca vaccine is approved for use in adults aged 18 and older. Some countries have placed restrictions on its use in older adults due to limited data on its efficacy in this age group.
• Blood clotting concerns
• There have been reports of rare cases of blood clotting disorders, including cerebral venous sinus thrombosis, following vaccination with the AstraZeneca vaccine. Health authorities have emphasized that the benefits of the vaccine outweigh the risks, and the incidence of these side effects is extremely rare.
• Approval and authorization
• The AstraZeneca vaccine has received emergency use authorization or full approval for use in many countries around the world, including the UK, EU, Australia, and India.
• Global distribution and supply
• AstraZeneca has partnered with various manufacturers and organizations to produce and distribute the vaccine on a global scale. The vaccine is being supplied to low- and middle-income countries through initiatives like COVAX to ensure equitable access.
• Effectiveness against variants
• Studies have shown that the AstraZeneca vaccine provides protection against the original strain of the SARS-CoV-2 virus as well as some of the variants of concern, although the efficacy may be slightly reduced against certain variants. Ongoing research is being conducted to assess the vaccine's effectiveness against emerging variants.